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Drug Interactions and Side Effects of Hydrochlorothiazide

Hydrochlorothiazide has 52 Side Effects total
31 are Life Threatening
4 Occur Most Frequently

Uses of Hydrochlorothiazide
 
USES:
This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Hydrochlorothiazide is a "water pill" (diuretic) that causes you to make more urine. This helps your body get rid of extra salt and water.

This medication also reduces extra fluid in the body (edema) caused by conditions such as heart failure, liver disease, or kidney disease. This can lessen symptoms such as shortness of breath or swelling in your ankles or feet.


Hydrochlorothiazide has 31 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Acid Base Problem with Low Chloride and Basic pH Blood - Hypochloremic Alkalosis is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Allergic Reaction causing Inflammation of Blood Vessels - Hypersensitivity Angiitis is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Closed Angle Glaucoma - Narrow Angle Glaucoma is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Gout is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Hemolytic Anemia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Hepatitis is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - High Amount of Calcium in the Blood - Hypercalcemia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - High Amount of Uric Acid in the Blood - Hyperuricemia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Imbalance in Body Salts like Potassium and Sodium - Disorder of Electrolytes is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Interstitial Nephritis is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Kidney Disease - Renal Disease is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Large Purple or Brown Skin Blotches - Purpura is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Low Amount of Magnesium in the Blood - Hypomagnesemia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Low Amount of Potassium in the Blood - Hypokalemia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Low Amount of Sodium in the Blood - Hyponatremia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Low Blood Counts due to Bone Marrow Failure - Aplastic Anemia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Nearsightedness - Myopia is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Systemic Lupus Erythematosus is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Hydrochlorothiazide
Critical Seriousness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Hydrochlorothiazide

Hydrochlorothiazide has 4 Most Frequently Occurring Side Effects
 
Acid Base Problem with Low Chloride and Basic pH Blood - Hypochloremic Alkalosis is a Frequently Occurring Side Effect of Hydrochlorothiazide
Imbalance in Body Salts like Potassium and Sodium - Disorder of Electrolytes is a Frequently Occurring Side Effect of Hydrochlorothiazide
Low Amount of Potassium in the Blood - Hypokalemia is a Frequently Occurring Side Effect of Hydrochlorothiazide
Low Amount of Sodium in the Blood - Hyponatremia is a Frequently Occurring Side Effect of Hydrochlorothiazide

Hydrochlorothiazide Drug-Drug Interactions
 
Hydrochlorothiazide has interactions of severe seriousness with 6 drug(s):
Hydrochlorothiazide has 1 severe interactions with Cisapride. Click here to see them
Hydrochlorothiazide has 1 severe interactions with Dofetilide. Click here to see them
Hydrochlorothiazide has 1 severe interactions with Propulsid. Click here to see them
Hydrochlorothiazide has 1 severe interactions with Solage. Click here to see them
Hydrochlorothiazide has 1 severe interactions with Tikosyn. Click here to see them
Hydrochlorothiazide has 1 severe interactions with Tretinoin-Mequinol. Click here to see them

Hydrochlorothiazide has interactions of serious seriousness with 49 drug(s).

Hydrochlorothiazide has interactions of moderate seriousness with 192 drug(s).

Hydrochlorothiazide has interactions of unknown seriousness with 0 drug(s).

Hydrochlorothiazide has 20 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Hydrochlorothiazide.

Hydrochlorothiazide Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Anuria - Absence of Urine Formation is a contraindication of Hydrochlorothiazide.

Relative Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Hydrochlorothiazide.

Azotemia is a contraindication of Hydrochlorothiazide.

Dehydration - Extreme Loss of Body Water is a contraindication of Hydrochlorothiazide.

Gout is a contraindication of Hydrochlorothiazide.

Hepatic Coma - Unconsciousness Resulting from Liver Cell Deterioration is a contraindication of Hydrochlorothiazide.

Hyperuricemia - High Amount of Uric Acid in the Blood is a contraindication of Hydrochlorothiazide.

Hypochloremic Alkalosis - Acid Base Problem with Low Chloride and Basic pH Blood is a contraindication of Hydrochlorothiazide.

Hypokalemia - Low Amount of Potassium in the Blood is a contraindication of Hydrochlorothiazide.

Hypomagnesemia - Low Amount of Magnesium in the Blood is a contraindication of Hydrochlorothiazide.

Hyponatremia - Low Amount of Sodium in the Blood is a contraindication of Hydrochlorothiazide.

Hypovolemia - Decreased Blood Volume is a contraindication of Hydrochlorothiazide.

Neonatal Hyperbilirubinemia - Yellowing of the Skin in a Newborn Child is a contraindication of Hydrochlorothiazide.

Secondary Narrow Angle Glaucoma - Angle-Closure Glaucoma caused by Another Disease is a contraindication of Hydrochlorothiazide.

Contraindication Warnings 

Diabetes Mellitus - Diabetes is a contraindication of Hydrochlorothiazide.

Hypercalcemia - High Amount of Calcium in the Blood is a contraindication of Hydrochlorothiazide.

Hypercholesterolemia - High Cholesterol is a contraindication of Hydrochlorothiazide.

Hyperparathyroidism - Increased Activity of the Parathyroid Gland is a contraindication of Hydrochlorothiazide.

Sympathectomy is a contraindication of Hydrochlorothiazide.

Systemic Lupus Erythematosus is a contraindication of Hydrochlorothiazide.

Hydrochlorothiazide has 5 related brands and strengths:
 
Hydrochlorothiazide 12.5 Mg Cap

Hydrochlorothiazide 12.5 Mg Tab

Hydrochlorothiazide 25 Mg Tab

Hydrochlorothiazide 50 Mg Tab

Microzide 12.5 Mg Cap

Hydrochlorothiazide - Symptoms of overdose may include
severe dizziness, weakness, fainting.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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