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Drug Interactions and Side Effects of Kaletra

Kaletra has 58 Side Effects total
28 are Life Threatening
6 Occur Most Frequently

Uses of Kaletra
 
Kaletra is also known by the generic name Lopinavir-Ritonavir


USES:
This combination product contains two medications, lopinavir and ritonavir. This product is used in combination with other medications to help control your HIV infection, thereby improving your quality of life. It also lowers your risk of getting HIV disease complications (e.g., opportunistic infections, cancer). Both lopinavir and ritonavir belong to a class of drugs known as HIV protease inhibitors. The ritonavir in this product helps the lopinavir to stay in your body. This effect builds up the amount of lopinavir in your body, increasing its effectiveness.

This lopinavir/ritonavir product is not a cure for HIV infection, and it does not prevent the spread of HIV to others through sexual contact or blood contamination (e.g., sharing used needles).


Kaletra has 28 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Anemia is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Atrial Fibrillation is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Atrioventricular Heart Block - Atrioventricular Block is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Blood Clot in a Deep Vein - Deep Venous Thrombosis is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Depression is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Diabetes - Diabetes Mellitus is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Enlarged Liver - Hepatomegaly is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Enlarged Spleen - Hypersplenism is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Erythema Multiforme is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Fluid in the Lungs - Pulmonary Edema is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Heart Attack - Myocardial Infarction is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Hepatitis is a Life Threatening Side Effect of Kaletra
Critical Seriousness - High Amount of Uric Acid in the Blood - Hyperuricemia is a Life Threatening Side Effect of Kaletra
Critical Seriousness - High Blood Sugar - Hyperglycemia is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Infection is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Prolonged P-R Interval observed on EKG - Prolonged PR Interval is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Small and Large Intestine Inflammation - Enterocolitis is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Toxic Epidermal Necrolysis is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Tumor - Neoplasm is a Life Threatening Side Effect of Kaletra
Critical Seriousness - Underactive Thyroid - Hypothyroidism is a Life Threatening Side Effect of Kaletra

Kaletra has 6 Most Frequently Occurring Side Effects
 
Diarrhea is a Frequently Occurring Side Effect of Kaletra
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Kaletra
Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Kaletra
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Kaletra
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Kaletra
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Kaletra

Kaletra has 26 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Kaletra.

Kaletra Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Kaletra.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Kaletra.

Relative Contraindications 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Kaletra.

Chronic Hepatitis C is a contraindication of Kaletra.

Chronic Type B Viral Hepatitis - Chronic Hepatitis B is a contraindication of Kaletra.

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Kaletra.

Diabetes Mellitus - Diabetes is a contraindication of Kaletra.

Disease of Liver - Liver Problems is a contraindication of Kaletra.

Hemophilia A is a contraindication of Kaletra.

Hemophilia B - Blood Clotting Disorder from Clotting Factor IX is a contraindication of Kaletra.

Hepatic Cirrhosis - Hardening of the Liver is a contraindication of Kaletra.

Hypertriglyceridemia - High Amount of Triglyceride in the Blood is a contraindication of Kaletra.

Hypokalemia - Low Amount of Potassium in the Blood is a contraindication of Kaletra.

Hypomagnesemia - Low Amount of Magnesium in the Blood is a contraindication of Kaletra.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Kaletra.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Kaletra.

Contraindication Warnings 

Cardiomyopathy - Disease of the Muscle of the Heart with Enlargement is a contraindication of Kaletra.

Complete Atrioventricular Block - Complete Heart Block is a contraindication of Kaletra.

Conduction Disorder of the Heart - Abnormal Heart Rhythm is a contraindication of Kaletra.

First Degree Atrioventricular Heart Block is a contraindication of Kaletra.

Hyperbilirubinemia - High Amount of Bilirubin in the Blood is a contraindication of Kaletra.

Hyperglycemia - High Blood Sugar is a contraindication of Kaletra.

Mixed Hyperlipidemia - Combined High Blood Cholesterol and Triglyceride Level is a contraindication of Kaletra.

Myocardial Ischemia - Disease of Inadequate Blood Flow to the Heart Muscle is a contraindication of Kaletra.

Second Degree Atrioventricular Heart Block is a contraindication of Kaletra.

Structural Disorder of Heart is a contraindication of Kaletra.

Kaletra has 6 related brands and strengths:
 
Kaletra 100 Mg-25 Mg Tab

Kaletra 200 Mg-50 Mg Tab

Kaletra 400 Mg-100 Mg/5 Ml Oral Soln

Lopinavir-Ritonavir 100 Mg-25 Mg Tab

Lopinavir-Ritonavir 200 Mg-50 Mg Tab

Lopinavir-Ritonavir 400 Mg-100 Mg/5 Ml Oral Soln

Kaletra - Symptoms of overdose may include
change in amount of urine; or numbness or tingling in the arms, hands, legs, or feet.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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