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Brief Intro
Video Part 1		 Brief Intro
Video Part 2		 Brochure Drug Store News
Heavy hITters		  

Drug Interactions and Side Effects of Lapatinib

Lapatinib has 20 Side Effects total
10 are Life Threatening
8 Occur Most Frequently
Click for a searchable interactive map of all Side Effects associated with Lapatinib

Uses of Lapatinib
 
USES:
Lapatinib is used together with another medication (capecitabine) to treat a certain type of breast cancer (HER2-positive) that has not responded to the standard treatment. It works by slowing or stopping the growth of cancer cells.


Lapatinib has 10 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Failure of the Left Ventricle of the Heart - Left Ventricular Failure is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Interstitial Pneumonitis is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Liver Problems - Disease of Liver is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Lung Tissue Problems - Interstitial Lung Disease is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Prolonged Q-T Interval on EKG - Prolonged QT Interval is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Tingling, Pain, Redness and Edema of Hands and Feet - Palmar-Plantar Erythrodysesthesia is a Life Threatening Side Effect of Lapatinib
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Lapatinib
Click for a searchable interactive map of all Life Threatening Side Effects associated with Lapatinib.

Lapatinib has 8 Most Frequently Occurring Side Effects
 
Diarrhea is a Frequently Occurring Side Effect of Lapatinib
Dry Skin is a Frequently Occurring Side Effect of Lapatinib
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Lapatinib
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Lapatinib
Low Energy - Fatigue is a Frequently Occurring Side Effect of Lapatinib
Rash - Skin Rash is a Frequently Occurring Side Effect of Lapatinib
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Lapatinib
Tingling, Pain, Redness and Edema of Hands and Feet - Palmar-Plantar Erythrodysesthesia is a Frequently Occurring Side Effect of Lapatinib
Click for a searchable interactive map of all Side Effects associated with Lapatinib

Lapatinib Drug-Drug Interactions
 
Lapatinib has interactions of severe seriousness with 6 drug(s):
Lapatinib has 1 severe interactions with Bepridil. Click here to see them
Lapatinib has 1 severe interactions with Efalizumab. Click here to see them
Lapatinib has 1 severe interactions with Natalizumab. Click here to see them
Lapatinib has 1 severe interactions with Raptiva. Click here to see them
Lapatinib has 1 severe interactions with Tysabri. Click here to see them
Lapatinib has 1 severe interactions with Vascor. Click here to see them

Lapatinib has interactions of serious seriousness with 424 drug(s).

Lapatinib has interactions of moderate seriousness with 355 drug(s).

Lapatinib has interactions of unknown seriousness with 0 drug(s).

Lapatinib has 13 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Lapatinib.

Lapatinib Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Interstitial Pneumonitis is a contraindication of Lapatinib.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Lapatinib.

Left Ventricular Failure - Failure of the Left Ventricle of the Heart is a contraindication of Lapatinib.

Pregnancy is a contraindication of Lapatinib.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Lapatinib.

Relative Contraindications 

Congenital Long QT Syndrome - Abnormal EKG with QT changes from Birth is a contraindication of Lapatinib.

Drug-Induced Hepatitis - Hepatitis caused by Drugs is a contraindication of Lapatinib.

Hypokalemia - Low Amount of Potassium in the Blood is a contraindication of Lapatinib.

Hypomagnesemia - Low Amount of Magnesium in the Blood is a contraindication of Lapatinib.

Prolonged QT Interval - Prolonged Q-T Interval on EKG is a contraindication of Lapatinib.

Severe Diarrhea is a contraindication of Lapatinib.

Torsades de Pointes - Very Rapid Heartbeat - Torsades de Pointes is a contraindication of Lapatinib.

Contraindication Warnings 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Lapatinib.

Lapatinib has 2 related brands and strengths:
 
Lapatinib 250 Mg Tab

Tykerb 250 Mg Tab

Lapatinib - Symptoms of overdose may include
severe diarrhea/vomiting.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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