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Drug Interactions and Side Effects of Niacin

Niacin has 46 Side Effects total
12 are Life Threatening
18 Occur Most Frequently

Uses of Niacin
 
USES:
Niacin is used in addition to a proper diet and exercise to help control levels of fats in the blood. It can help lower "bad" cholesterol and fats (e.g., LDL, triglycerides) and raise "good" cholesterol (HDL). In general, this drug is used after your blood fat levels have not been fully controlled by other treatment (e.g., diet changes, exercise, decreasing alcohol intake, stopping smoking, weight loss if overweight, and controlling blood sugar if diabetic). It may be used with or without other medications.

Lowering "bad" cholesterol/triglycerides and raising "good" cholesterol may help decrease the risk for strokes and heart attacks. Lowering fats may also help reduce the risk of pancreas problems (pancreatitis) in people at risk. Niacin is also known as vitamin B-3 (nicotinic acid), one of the B-complex vitamins.


Niacin has 12 Life Threatening (Critical) Side Effects
 
Critical Seriousness - A Spasm of the Larynx - Laryngismus is a Life Threatening Side Effect of Niacin
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Niacin
Critical Seriousness - Blockage of Normal Bile Flow - Cholestasis is a Life Threatening Side Effect of Niacin
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Niacin
Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Niacin
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Niacin
Critical Seriousness - Life Threatening Allergic Reaction - Anaphylaxis is a Life Threatening Side Effect of Niacin
Critical Seriousness - Muscle Disease - Myopathy is a Life Threatening Side Effect of Niacin
Critical Seriousness - Numbness and Tingling - Paresthesia is a Life Threatening Side Effect of Niacin
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Niacin
Critical Seriousness - Visible Water Retention - Edema is a Life Threatening Side Effect of Niacin
Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Niacin

Niacin has 18 Most Frequently Occurring Side Effects
 
Abnormal Heart Rhythm - Conduction Disorder of the Heart is a Frequently Occurring Side Effect of Niacin
Cough is a Frequently Occurring Side Effect of Niacin
Diarrhea is a Frequently Occurring Side Effect of Niacin
Dizzy - Dizziness is a Frequently Occurring Side Effect of Niacin
Dry Eye is a Frequently Occurring Side Effect of Niacin
Dry Skin is a Frequently Occurring Side Effect of Niacin
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Niacin
Feeling Faint - Fainting is a Frequently Occurring Side Effect of Niacin
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Niacin
High Amount of Uric Acid in the Blood - Hyperuricemia is a Frequently Occurring Side Effect of Niacin
High Blood Sugar - Hyperglycemia is a Frequently Occurring Side Effect of Niacin
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Niacin
Inflammation of the Nose - Rhinitis is a Frequently Occurring Side Effect of Niacin
Itching - Pruritus of Skin is a Frequently Occurring Side Effect of Niacin
Muscle Pain - Myalgia is a Frequently Occurring Side Effect of Niacin
Temporary Redness of Face and Neck - Flushing is a Frequently Occurring Side Effect of Niacin
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Niacin
Worsening of Peptic Ulcer - Exacerbation of Peptic Ulcer is a Frequently Occurring Side Effect of Niacin

Niacin Drug-Drug Interactions
 
Niacin has interactions of severe seriousness with 0 drug(s):

Niacin has interactions of serious seriousness with 29 drug(s).

Niacin has interactions of moderate seriousness with 0 drug(s).

Niacin has interactions of unknown seriousness with 0 drug(s).

Niacin has 15 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Niacin.

Niacin Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Arterial Hemorrhage - Bleeding from an Artery is a contraindication of Niacin.

Disease of Liver - Liver Problems is a contraindication of Niacin.

Peptic Ulcer - Ulcer from Stomach Acid is a contraindication of Niacin.

Relative Contraindications 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Niacin.

Alcoholism - Habit of Drinking Too Much Alcohol is a contraindication of Niacin.

Blood Coagulation Disorder - Blood Clotting Disorder is a contraindication of Niacin.

Myocardial Infarction - Heart Attack is a contraindication of Niacin.

Unstable Angina Pectoris - Unpredictable Severe Constricting Chest Pain is a contraindication of Niacin.

Contraindication Warnings 

Coronary Artery Disease - Disease of the Arteries of the Heart is a contraindication of Niacin.

Diabetes Mellitus - Diabetes is a contraindication of Niacin.

Gout is a contraindication of Niacin.

Hyperglycemia - High Blood Sugar is a contraindication of Niacin.

Hypophosphatemia - Low Amount of Phosphate in the Blood is a contraindication of Niacin.

Hypotension - Abnormally Low Blood Pressure is a contraindication of Niacin.

Severe Thrombocytopenia - Severely Decreased Platelets is a contraindication of Niacin.

Niacin has 25 related brands and strengths:
 
Endur-Acin 250 Mg Tab

Endur-Acin 500 Mg Tab

Niacin 100 Mg Tab

Niacin 250 Mg Tab

Niacin 50 Mg Tab

Niacin 500 Mg Tab

Niacin Er 1,000 Mg 24 Hr Tab

Niacin Er 1,000 Mg Tab

Niacin Er 125 Mg Cap

Niacin Er 250 Mg Cap

Niacin Er 250 Mg Tab

Niacin Er 400 Mg Cap

Niacin Er 500 Mg 24 Hr Tab

Niacin Er 500 Mg Cap

Niacin Er 500 Mg Tab

Niacin Er 750 Mg 24 Hr Tab

Niacin Er 750 Mg Tab

Niacin Oral Powder

Niacor 500 Mg Tab

Niaspan Extended-Release 1,000 Mg 24 Hr Tab

Niaspan Extended-Release 500 Mg 24 Hr Tab

Niaspan Extended-Release 750 Mg 24 Hr Tab

Slo-Niacin 250 Mg Tab

Slo-Niacin 500 Mg Tab

Slo-Niacin 750 Mg Tab

Niacin - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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