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Drug Interactions and Side Effects of Pegasys

Pegasys has 58 Side Effects total
23 are Life Threatening
28 Occur Most Frequently

Uses of Pegasys
 
Pegasys is also known by the generic name Peginterferon Alfa-2a


USES:
Peginterferon alfa-2a is used alone or in combination with ribavirin to treat chronic hepatitis C, a viral infection of the liver. It is also used to treat chronic hepatitis B infection.

This medication reduces the amount of hepatitis C virus in the body and helps the body's immune system fight the infection. It is not known if peginterferon can cure hepatitis C virus infections (permanently eliminate the virus from your body). It is also not known if this drug can prevent you from passing the virus to others. Practice "safe sex" (including the use of latex condoms) to lower the risk of passing the virus to others.


Pegasys has 23 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Bacterial Infection of Blood or Tissues affecting the Whole Body - Bacterial Septicemia is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Bacterial Infection of the Kidney and Renal Pelvis - Pyelonephritis is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Bone Infection and Inflamation - Osteomyelitis is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Decreased Number of Lymphocytes in the Blood - Lymphopenia is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Depression is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Detachment of the Retina of the Eye - Retinal Detachment is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Fever is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Heart Valve Infection - Endocarditis is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Increased Pressure of Pulmonary Circulation - Pulmonary Hypertension is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Infection caused by Bacteria - Bacterial Infection is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Infection is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Mental Disorder with Loss of Normal Personality & Reality - Psychotic Disorder is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Numbness, Tingling or Pain of Hands or Feet - Peripheral Neuropathy is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Pneumonia is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Skin Rash with Sloughing - Exfoliative Dermatitis is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Stevens-Johnson Syndrome is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Stroke - Cerebrovascular Accident is a Life Threatening Side Effect of Pegasys
Critical Seriousness - Underactive Thyroid - Hypothyroidism is a Life Threatening Side Effect of Pegasys

Pegasys has 28 Most Frequently Occurring Side Effects
 
Anxious - Anxiety is a Frequently Occurring Side Effect of Pegasys
Backache - Back Pain is a Frequently Occurring Side Effect of Pegasys
Cannot Focus Thoughts - Concentration Difficulty is a Frequently Occurring Side Effect of Pegasys
Chills is a Frequently Occurring Side Effect of Pegasys
Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Pegasys
Decreased Neutrophils a Type of White Blood Cell - Neutropenic Disorder is a Frequently Occurring Side Effect of Pegasys
Depression is a Frequently Occurring Side Effect of Pegasys
Diarrhea is a Frequently Occurring Side Effect of Pegasys
Dizzy - Dizziness is a Frequently Occurring Side Effect of Pegasys
Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Pegasys
Easily Angered or Annoyed - Irritability is a Frequently Occurring Side Effect of Pegasys
Excessive Sweating - Hyperhidrosis is a Frequently Occurring Side Effect of Pegasys
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Pegasys
Feeling Weak - General Weakness is a Frequently Occurring Side Effect of Pegasys
Fever is a Frequently Occurring Side Effect of Pegasys
Hair Loss - Alopecia is a Frequently Occurring Side Effect of Pegasys
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Pegasys
Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Frequently Occurring Side Effect of Pegasys
Itching - Pruritus of Skin is a Frequently Occurring Side Effect of Pegasys
Joint Pain - Arthralgia is a Frequently Occurring Side Effect of Pegasys
Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Pegasys
Low Energy - Fatigue is a Frequently Occurring Side Effect of Pegasys
Muscle Pain - Myalgia is a Frequently Occurring Side Effect of Pegasys
Nervous - Nervousness is a Frequently Occurring Side Effect of Pegasys
Pain is a Frequently Occurring Side Effect of Pegasys
Signs and Symptoms at Injection Site - Injection Site Sequelae is a Frequently Occurring Side Effect of Pegasys
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Pegasys
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Pegasys

Pegasys Drug-Drug Interactions
 
Pegasys has interactions of severe seriousness with 0 drug(s):

Pegasys has interactions of serious seriousness with 6 drug(s).

Pegasys has interactions of moderate seriousness with 185 drug(s).

Pegasys has interactions of unknown seriousness with 0 drug(s).

Pegasys has 26 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Pegasys.

Pegasys Subcutaneous Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Pegasys.

Aplastic Anemia - Low Blood Counts due to Bone Marrow Failure is a contraindication of Pegasys.

Autoimmune Hepatitis - Liver Inflammation caused by Body's Own Immune Response is a contraindication of Pegasys.

Hemorrhagic Colitis - Inflammation of the Large Intestine with Bleeding is a contraindication of Pegasys.

Ischemic Colitis - Insufficient Blood Supply to the Colon is a contraindication of Pegasys.

Pregnancy is a contraindication of Pegasys.

Relative Contraindications 

Colitis - Inflammation of the Large Intestine is a contraindication of Pegasys.

Depression is a contraindication of Pegasys.

Psychiatric Disturbance - Mental Disturbance is a contraindication of Pegasys.

Pulmonary Disease - Lung Disease is a contraindication of Pegasys.

Retinal Disorder - Disease of the Retina of the Eye is a contraindication of Pegasys.

Retinal Thrombosis - A Blood Clot within the Blood Vessels of the Eye is a contraindication of Pegasys.

Severe Anemia is a contraindication of Pegasys.

Severe Infection is a contraindication of Pegasys.

Severe Neutropenic Disorder - Severely Decreased Levels of Neutrophils in the Blood is a contraindication of Pegasys.

Severe Renal Disease - Serious Kidney Problems is a contraindication of Pegasys.

Severe Thrombocytopenia - Severely Decreased Platelets is a contraindication of Pegasys.

Contraindication Warnings 

Autoimmune Disease - Disease in which Body has Immune Response Against Itself is a contraindication of Pegasys.

Diabetes Mellitus - Diabetes is a contraindication of Pegasys.

HIV Infection - HIV is a contraindication of Pegasys.

Hyperglycemia - High Blood Sugar is a contraindication of Pegasys.

Hyperthyroidism - Overactive Thyroid Gland is a contraindication of Pegasys.

Hypoglycemic Disorder - Low Blood Sugar is a contraindication of Pegasys.

Hypothyroidism - Underactive Thyroid is a contraindication of Pegasys.

Peripheral Neuropathy - Numbness, Tingling or Pain of Hands or Feet is a contraindication of Pegasys.

Transplantation Procedure - Transplant of an Organ is a contraindication of Pegasys.

Pegasys has 4 related brands and strengths:
 
Pegasys 180 Mcg/Ml Sub-Q

Pegasys Convenience Pack 180 Mcg/0.5 Ml Sub-Q Kit

Peginterferon Alfa-2a 180 Mcg/0.5 Ml Sub-Q Kit

Peginterferon Alfa-2a 180 Mcg/Ml Sub-Q

Pegasys - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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