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Drug Interactions and Side Effects of Phenergan

Phenergan has 46 Side Effects total
18 are Life Threatening
16 Occur Most Frequently

Uses of Phenergan
 
Phenergan is also known by the generic name Promethazine


USES:
Promethazine is used to prevent and treat nausea and vomiting related to certain conditions (e.g., motion sickness, before/after surgery). It is also used to treat allergic symptoms such as rash, itching, and runny nose. It may be used for a short time to treat a runny nose due to the common cold. It may also be used to help you feel calmer before/after surgery or to help certain narcotic pain relievers (e.g., meperidine) work better.

Promethazine is an antihistamine. It works by blocking a certain natural substance (histamine) that your body makes during an allergic reaction. Its other effects (e.g., anti-nausea, calming, pain relief) may work by affecting other natural substances (e.g., acetylcholine) and by acting directly on certain parts of the brain.

Cough-and-cold products have not been shown to be safe or effective in children younger than 6 years. Therefore, do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. Some products (such as long-acting tablets/capsules) are not recommended for use in children younger than 12 years. Ask your doctor or pharmacist for more details about using your product safely.

These products do not cure or shorten the length of the common cold and may cause serious side effects. To decrease the risk for serious side effects, carefully follow all dosage directions. Do not use this product to make a child sleepy. Do not give other cough-and-cold medication that might contain the same or similar ingredients (see also Drug Interactions section). Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray).


Phenergan has 18 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Asthma - Bronchial Asthma is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Decreased White Blood Cells - Leukopenia is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Deficiency of Granulocytes a Type of White Blood Cell - Agranulocytosis is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Delirium is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Extrapyramidal Reaction - Extrapyramidal Disease is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Giant Hives - Angioedema is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Hallucination - Hallucinations is a Life Threatening Side Effect of Phenergan
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Lower Seizure Threshold is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Neuroleptic Malignant Syndrome is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Periods of Not Breathing - Apnea is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Significant Decrease in Lung Function - Respiratory Depression is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Slow Heartbeat - Bradycardia is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Thrombotic Thrombocytopenic Purpura is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Yellowing of Skin or Eyes from Bile Flow Problems - Obstructive Hyperbilirubinemia is a Life Threatening Side Effect of Phenergan
Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Phenergan

Phenergan has 16 Most Frequently Occurring Side Effects
 
Abnormally Low Blood Pressure - Hypotension is a Frequently Occurring Side Effect of Phenergan
An Increase in the Thickness of Lung Secretions - Thick Bronchial Secretions is a Frequently Occurring Side Effect of Phenergan
Blurred Vision is a Frequently Occurring Side Effect of Phenergan
Confused - Impaired Cognition is a Frequently Occurring Side Effect of Phenergan
Dizzy - Dizziness is a Frequently Occurring Side Effect of Phenergan
Drowsiness - Drowsy is a Frequently Occurring Side Effect of Phenergan
Dry Mouth - Xerostomia is a Frequently Occurring Side Effect of Phenergan
Easily Angered or Annoyed - Irritability is a Frequently Occurring Side Effect of Phenergan
Fast Heartbeat - Tachyarrhythmia is a Frequently Occurring Side Effect of Phenergan
Nervous - Nervousness is a Frequently Occurring Side Effect of Phenergan
Nightmares is a Frequently Occurring Side Effect of Phenergan
Over Excitement - Excitement is a Frequently Occurring Side Effect of Phenergan
Problems with Eyesight - Visual Changes is a Frequently Occurring Side Effect of Phenergan
Rash - Skin Rash is a Frequently Occurring Side Effect of Phenergan
Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Phenergan
Sun-Sensitive Skin - Skin Photosensitivity is a Frequently Occurring Side Effect of Phenergan

Phenergan Drug-Drug Interactions
 
Phenergan has interactions of severe seriousness with 21 drug(s):
Phenergan has 1 severe interactions with Amipaque. Click here to see them
Phenergan has 1 severe interactions with Amipaque W/Diluent. Click here to see them
Phenergan has 2 severe interactions with Cisapride. Click here to see them
Phenergan has 1 severe interactions with Dronedarone. Click here to see them
Phenergan has 1 severe interactions with Fareston. Click here to see them
Phenergan has 1 severe interactions with Grepafloxacin. Click here to see them
Phenergan has 1 severe interactions with Halfan. Click here to see them
Phenergan has 1 severe interactions with Halofantrine. Click here to see them
Phenergan has 1 severe interactions with Meridia. Click here to see them
Phenergan has 1 severe interactions with Metrizamide. Click here to see them
Phenergan has 1 severe interactions with Multaq. Click here to see them
Phenergan has 1 severe interactions with Orap. Click here to see them
Phenergan has 1 severe interactions with Pimozide. Click here to see them
Phenergan has 1 severe interactions with Propulsid. Click here to see them
Phenergan has 1 severe interactions with Raxar. Click here to see them
Phenergan has 1 severe interactions with Sibutramine. Click here to see them
Phenergan has 1 severe interactions with Solage. Click here to see them
Phenergan has 1 severe interactions with Sparfloxacin. Click here to see them
Phenergan has 1 severe interactions with Toremifene. Click here to see them
Phenergan has 1 severe interactions with Tretinoin-Mequinol. Click here to see them
Phenergan has 1 severe interactions with Zagam. Click here to see them

Phenergan has interactions of serious seriousness with 0 drug(s).

Phenergan has interactions of moderate seriousness with 969 drug(s).

Phenergan has interactions of unknown seriousness with 0 drug(s).

Phenergan has 22 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Phenergan.

Phenergan Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Coma is a contraindication of Phenergan.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Phenergan.

Neuroleptic Malignant Syndrome is a contraindication of Phenergan.

Respiratory Depression - Significant Decrease in Lung Function is a contraindication of Phenergan.

Relative Contraindications 

Benign Prostatic Hypertrophy - Enlarged Prostate is a contraindication of Phenergan.

Bladder Outflow Obstruction - Blockage of Urinary Bladder is a contraindication of Phenergan.

CNS Depression - Abnormal Nervous System Function Affecting Mental Alertness is a contraindication of Phenergan.

Chronic Idiopathic Constipation - Chronic Difficulty having a Bowel Movement is a contraindication of Phenergan.

Chronic Obstructive Pulmonary Disease - Chronic Obstructive Lung Disease is a contraindication of Phenergan.

Narrow Angle Glaucoma - Closed Angle Glaucoma is a contraindication of Phenergan.

Pyloroduodenal Obstruction - Narrowing of Opening Between Stomach and Small Intestine is a contraindication of Phenergan.

Sleep Apnea - Temporarily Stops Breathing While Sleeping is a contraindication of Phenergan.

Stenosing Peptic Ulcer is a contraindication of Phenergan.

Contraindication Warnings 

Bone Marrow Depression - Decreased Function of Bone Marrow is a contraindication of Phenergan.

CNS Disorder - Diseases of the Brain and Spinal Cord is a contraindication of Phenergan.

Disease of Cardiovascular System - Disease of the Heart and Blood Vessels is a contraindication of Phenergan.

Disease of Liver - Liver Problems is a contraindication of Phenergan.

Encephalopathy - Any Disorder of the Brain is a contraindication of Phenergan.

Epilepsy - Epileptic Seizure is a contraindication of Phenergan.

Gastrointestinal Obstruction - Stomach or Intestine Blockage is a contraindication of Phenergan.

Hyperbilirubinemia - High Amount of Bilirubin in the Blood is a contraindication of Phenergan.

Lower Seizure Threshold is a contraindication of Phenergan.

Phenergan has 17 related brands and strengths:
 
Phenadoz 12.5 Mg Rectal Suppository

Phenadoz 25 Mg Rectal Suppository

Phenergan 25 Mg/Ml Injection

Phenergan 50 Mg/Ml Injection

Promethazine 12.5 Mg Rectal Suppository

Promethazine 12.5 Mg Tab

Promethazine 25 Mg Rectal Suppository

Promethazine 25 Mg Tab

Promethazine 25 Mg/Ml Injection

Promethazine 25 Mg/Ml Syringe

Promethazine 50 Mg Rectal Suppository

Promethazine 50 Mg Tab

Promethazine 50 Mg/Ml Injection

Promethazine 6.25 Mg/5 Ml Syrup

Promethegan 12.5 Mg Rectal Suppository

Promethegan 25 Mg Rectal Suppository

Promethegan 50 Mg Rectal Suppository

Phenergan - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include severe dizziness, fainting, very slow/shallow breathing, loss of consciousness, muscle stiffness/twitching, hot dry skin, widened pupils.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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