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Drug Interactions and Side Effects of Tysabri

Tysabri has 47 Side Effects total
23 are Life Threatening
5 Occur Most Frequently

Uses of Tysabri
 
Tysabri is also known by the generic name Natalizumab


USES:
This medication is used to treat a type of multiple sclerosis that occurs when symptoms appear in cycles of worsening and improvement (relapsing/remitting multiple sclerosis-MS). It is not a cure for MS, but it is thought to help by preventing your immune system from attacking the nerves in your brain and spinal cord. It helps decrease the number of episodes of worsening and may prevent or delay disability.

Natalizumab is also used to treat a bowel condition called Crohn's disease (CD) when it is moderate to severe and/or keeps coming back. It is not a cure for CD, but it is thought to work by preventing your immune system from causing inflammation/swelling within your bowels.

Natalizumab is a protein called a monoclonal antibody.


Tysabri has 23 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Allergic Reaction caused by a Drug - Hypersensitivity Drug Reactions is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Appendicitis is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Chest Tightness is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Depression is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Disease in the White Matter Area of the Brain - Leukoencephalopathy is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Gallstones - Biliary Calculus is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Tysabri
Critical Seriousness - High Amount of Bilirubin in the Blood - Hyperbilirubinemia is a Life Threatening Side Effect of Tysabri
Critical Seriousness - High Blood Pressure - Hypertension is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Hives - Urticaria is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Increased Risk of Bleeding is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Inflammation of Skin caused by an Allergy - Allergic Dermatitis is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Inflammation of the Tonsils - Tonsillitis is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Ovarian Cyst is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Progressive Disease in the White Matter of the Brain - Progressive Multifocal Leukoencephalopathy is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Rash - Skin Rash is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Reaction due to an Allergy - Allergic Reactions is a Life Threatening Side Effect of Tysabri
Critical Seriousness - The Flu - Influenza is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Tysabri
Critical Seriousness - Urinary Tract Infection - Urinary Tract Infections is a Life Threatening Side Effect of Tysabri

Tysabri has 5 Most Frequently Occurring Side Effects
 
Depression is a Frequently Occurring Side Effect of Tysabri
Head Pain - Headache Disorder is a Frequently Occurring Side Effect of Tysabri
Low Energy - Fatigue is a Frequently Occurring Side Effect of Tysabri
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Tysabri
Urinary Tract Infection - Urinary Tract Infections is a Frequently Occurring Side Effect of Tysabri

Tysabri has 9 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Tysabri.

Tysabri Intravenous Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Jaundice - Yellowing of Skin or Eyes from Liver Problems is a contraindication of Tysabri.

Lactating Mother - A Mother who is Producing Milk and Breastfeeding is a contraindication of Tysabri.

Progressive Multifocal Leukoencephalopathy - Progressive Disease in the White Matter of the Brain is a contraindication of Tysabri.

Severe Hepatic Disease - Severe Liver Disease is a contraindication of Tysabri.

Relative Contraindications 

Abnormal Hepatic Function Tests - Abnormal Liver Function Tests is a contraindication of Tysabri.

Disorder of Immune Function - Condition Resulting from a Defective Immune System is a contraindication of Tysabri.

Hyperbilirubinemia - High Amount of Bilirubin in the Blood is a contraindication of Tysabri.

Immunosuppression - Reduction in the Body's Resistance to Infection is a contraindication of Tysabri.

Contraindication Warnings 

Infection is a contraindication of Tysabri.

Tysabri has 2 related brands and strengths:
 
Natalizumab 300 Mg/15 Ml Iv

Tysabri 300 Mg/15 Ml Iv

Tysabri - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US National Poison Hotline at 1-800-222-1222. Canada residents can call a provincial poison control center.

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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