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Drug Interactions and Side Effects of Valproic Acid

Valproic Acid has 49 Side Effects total
20 are Life Threatening
17 Occur Most Frequently

Uses of Valproic Acid
 
USES:
This medication is used to treat seizure disorders, mental/mood conditions (such as manic phase of bipolar disorder), and to prevent migraine headaches. It works by restoring the balance of certain natural substances (neurotransmitters) in the brain.


Valproic Acid has 20 Life Threatening (Critical) Side Effects
 
Critical Seriousness - Abnormal Liver Function Tests - Abnormal Hepatic Function Tests is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Acute Inflammation of the Pancreas - Acute Pancreatitis is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Acute Liver Failure - Acute Hepatic Failure is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Decrease in the Ability of Platelet Cells to Clot - Platelet Aggregation Inhibition is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Decreased Blood Platelets - Thrombocytopenic Disorder is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Double Vision - Diplopia is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Fluid Retention in the Legs, Feet, Arms or Hands - Peripheral Edema is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Having Thoughts of Suicide - Suicidal Ideation is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Hepatitis caused by Drugs - Drug-Induced Hepatitis is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - High Amount of Ammonium in the Blood - Hyperammonemia is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Involuntary Eye Movement - Nystagmus is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Low Body Temperature - Hypothermia is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Mental Impairment is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Mood Changes is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Problem Behavior - Behavioral Disorders is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Puffy Face from Water Retention - Facial Edema is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Seeing Spots - Visual Disturbance of Seeing Spots is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Swollen Lymph Nodes - Lymphadenopathy is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Trouble Breathing - Dyspnea is a Life Threatening Side Effect of Valproic Acid
Critical Seriousness - Yellowing of Skin or Eyes from Liver Problems - Jaundice is a Life Threatening Side Effect of Valproic Acid

Valproic Acid has 17 Most Frequently Occurring Side Effects
 
Chronic Trouble Sleeping - Insomnia is a Frequently Occurring Side Effect of Valproic Acid
Diarrhea is a Frequently Occurring Side Effect of Valproic Acid
Dizzy - Dizziness is a Frequently Occurring Side Effect of Valproic Acid
Drowsiness - Drowsy is a Frequently Occurring Side Effect of Valproic Acid
Feel Like Throwing Up - Nausea is a Frequently Occurring Side Effect of Valproic Acid
Hair Loss - Alopecia is a Frequently Occurring Side Effect of Valproic Acid
Indigestion - Dyspepsia is a Frequently Occurring Side Effect of Valproic Acid
Infection is a Frequently Occurring Side Effect of Valproic Acid
Involuntary Quivering - Tremors is a Frequently Occurring Side Effect of Valproic Acid
Irregular Periods - Irregular Menstrual Periods is a Frequently Occurring Side Effect of Valproic Acid
Loss of Appetite - Anorexia is a Frequently Occurring Side Effect of Valproic Acid
Ringing in the Ears - Tinnitus is a Frequently Occurring Side Effect of Valproic Acid
Stomach Cramps - Abdominal Pain with Cramps is a Frequently Occurring Side Effect of Valproic Acid
Throat Irritation - Pharyngitis is a Frequently Occurring Side Effect of Valproic Acid
Throwing Up - Vomiting is a Frequently Occurring Side Effect of Valproic Acid
Weight Gain is a Frequently Occurring Side Effect of Valproic Acid
Weight Loss is a Frequently Occurring Side Effect of Valproic Acid

Valproic Acid Drug-Drug Interactions
 
Valproic Acid has interactions of severe seriousness with 0 drug(s):

Valproic Acid has interactions of serious seriousness with 24 drug(s).

Valproic Acid has interactions of moderate seriousness with 1075 drug(s).

Valproic Acid has interactions of unknown seriousness with 11 drug(s).

Valproic Acid has 20 Condition Contraindications
 
If you have any of these Conditions then you should carefully evaluate the risks of taking Valproic Acid.

Valproic Acid Oral Contraindications
(grouped by decreasing seriouosness level)

Absolute Contraindications 

Acute Pancreatitis - Acute Inflammation of the Pancreas is a contraindication of Valproic Acid.

Arginase Deficiency is a contraindication of Valproic Acid.

Arginosuccinate Lyase Deficiency - Inherited Deficiency of Arginosuccinate Lyase is a contraindication of Valproic Acid.

Carbamyl Phosphate Synthetase Deficiency - Inherited Deficiency of Carbamyl Phosphate Synthetase is a contraindication of Valproic Acid.

Chronic Pancreatitis - Chronic Inflammation of the Pancreas is a contraindication of Valproic Acid.

Citrullinemia is a contraindication of Valproic Acid.

Disease of Liver - Liver Problems is a contraindication of Valproic Acid.

Ornithine Carbamyltransferase Deficiency is a contraindication of Valproic Acid.

Pregnancy is a contraindication of Valproic Acid.

Valproic Acid Toxicity - Poisoning by Drug Valproic Acid is a contraindication of Valproic Acid.

Relative Contraindications 

Hyperammonemia - High Amount of Ammonium in the Blood is a contraindication of Valproic Acid.

Hypothermia - Low Body Temperature is a contraindication of Valproic Acid.

Porphyria is a contraindication of Valproic Acid.

Suicidal Ideation - Having Thoughts of Suicide is a contraindication of Valproic Acid.

Thrombocytopenic Disorder - Decreased Blood Platelets is a contraindication of Valproic Acid.

Contraindication Warnings 

Blood Dyscrasias - Blood Disorder is a contraindication of Valproic Acid.

Depression is a contraindication of Valproic Acid.

Hypoalbuminemia - Low Amount of Albumin Proteins in the Blood is a contraindication of Valproic Acid.

Organic Mental Disorder - Dysfunction of the Brain is a contraindication of Valproic Acid.

Renal Disease - Kidney Disease is a contraindication of Valproic Acid.

Valproic Acid has 8 related brands and strengths:
 
Depakene 250 Mg Cap

Stavzor 125 Mg Cap

Stavzor 250 Mg Cap

Stavzor 500 Mg Cap

Valproic Acid 125 Mg Cap, Delayed Release

Valproic Acid 250 Mg Cap

Valproic Acid 250 Mg Cap, Delayed Release

Valproic Acid 500 Mg Cap, Delayed Release

Valproic Acid - Symptoms of overdose may include
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include excessive drowsiness, coma, irregular/slowed/skipped heart beats (heart block).

Contact poison control
If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.

IMPORTANT NOTICE: The drug information contained in this application is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not exhaustive and is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. The display and use of this drug information is subject to express terms of use. By continuing to view the drug information on this site, you agree to abide by such terms of use.
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